Presented by NUWA Fertility at the 2022 Taiwan Society for Reproductive Medicine (TSRM) Annual Meeting
At the 2022 TSRM annual conference, NUWA Fertility presented an oral research report confirming that the AI-based CHLOE scoring system demonstrates strong potential in predicting clinical pregnancy rates following day-5 single embryo transfer (SET). This advancement brings new promise to improving the precision and objectivity of embryo selection in IVF treatment.
Background: How AI Is Transforming Embryo Selection
In IVF, selecting the embryo with the highest implantation potential is critical to achieving success. Traditionally, embryo assessment relies on embryologists’ expertise and visual morphological grading. However, this method is subjective and may vary across practitioners. To improve objectivity and consistency, AI-powered embryo evaluation tools like CHLOE have been developed.
This study investigates the effectiveness of the CHLOE scoring system in predicting clinical pregnancy outcomes after day-5 single blastocyst transfer.
Methodology: Evaluating the Correlation Between CHLOE Scores and Pregnancy Rates
The research team analyzed data from 96 day-5 single blastocyst transfers. Each embryo was assigned a CHLOE score and categorized into four distinct score groups. Clinical pregnancy rates were then calculated for each group to assess the correlation between CHLOE scores and pregnancy outcomes. The study aimed to determine whether CHLOE scores could serve as a reliable predictor of success, thereby improving the consistency and efficiency of embryo selection.
Results: Strong Positive Correlation Between CHLOE Scores and Clinical Pregnancy Rates
The study revealed a significant and strong positive correlation between CHLOE scores and clinical pregnancy rates following day-5 SET.
In other words, embryos with higher CHLOE scores had a greater likelihood of leading to a successful pregnancy. This supports the clinical value of using the CHLOE system as an evidence-based reference in embryo selection.
Clinical Implications: Enhancing Precision and Consistency in Embryo Selection
The study concludes that the AI-powered CHLOE scoring system is highly correlated with clinical pregnancy outcomes in day-5 single blastocyst transfers. By integrating CHLOE into clinical practice, embryologists can assess embryo viability more objectively and accurately, enhancing both the consistency and efficiency of embryo selection.
This technology may ultimately contribute to higher IVF success rates and help more couples struggling with infertility achieve their family-building goals.
NUWA Fertility is actively adopting cutting-edge technologies to advance embryo assessment and IVF success. The integration of the CHLOE AI scoring system represents a significant step forward in optimizing embryo selection, allowing us to deliver higher-quality, more personalized IVF care to our patients.